| World Food Programme UN agency | South Sudan | US$44.1m |
| International Organization for Migration UN agency | South Sudan | US$15.7m |
| United Nations High Commissioner for Refugees UN agency | South Sudan | US$12.1m |
| United Nations Children's Fund UN agency | South Sudan | US$11.0m |
| Healthcare Foundation Organization National / local NGO | South Sudan | US$6.3m |
| World Health Organization UN agency | South Sudan | US$6.0m |
| Norwegian Refugee Council International NGO | South Sudan | US$4.6m |
| Women Agency for Resilience and Transformation National / local NGO | South Sudan | US$3.9m |
| Danish Refugee Council International NGO | South Sudan | US$3.6m |
| ACT Alliance / Norwegian Church Aid International NGO | South Sudan | US$3.6m |
| John Dau Foundation International NGO | South Sudan | US$3.4m |
| Relief International International NGO | South Sudan | US$3.4m |
| Coalition for Humanity South Sudan National / local NGO | South Sudan | US$3.3m |
| Christian Mission for Development National / local NGO | South Sudan | US$3.2m |
| World Vision South Sudan Other | South Sudan | US$3.1m |
| International Medical Corps UK Other | South Sudan | US$2.8m |
| GOAL International NGO | South Sudan | US$2.8m |
| Save the Children International NGO | South Sudan | US$2.5m |
| Concern Worldwide International NGO | South Sudan | US$2.5m |
| International Rescue Committee International NGO | South Sudan | US$2.0m |
| For Afrika to Thrive International NGO | South Sudan | US$1.7m |
| Solidarités International International NGO | South Sudan | US$1.5m |
| Medicair - South Sudan National / local NGO | South Sudan | US$1.3m |
| Christian Mission Aid International NGO | South Sudan | US$1.2m |
| International NGOs (Confidential) International NGO | South Sudan | US$1.2m |
| Reach Africa Organization National / local NGO | South Sudan | US$1.1m |
| World Relief International NGO | South Sudan | US$1.1m |
| United Nations Population Fund UN agency | South Sudan | US$1.0m |
| Catholic Medical Missons Board International NGO | South Sudan | US$1.0m |
| United Nations Office for Project Services UN agency | South Sudan | US$972.0k |
| Oxfam GB Other | South Sudan | US$700.0k |
| ACT Alliance / Lutheran World Federation International NGO | South Sudan | US$689.6k |
| Cordaid International International NGO | South Sudan | US$650.0k |
| Humanitarian and Development Consortium National / local NGO | South Sudan | US$600.0k |
| Agency for Technical Cooperation and Development International NGO | South Sudan | US$450.0k |
| Community Aid for Relief and Development National / local NGO | South Sudan | US$400.0k |
| Children Aid South Sudan National / local NGO | South Sudan | US$342.0k |